CBD Entourage Effect

CBD Entourage Effect

Have you ever come across term - Cannabis "entourage effect" ? 

Below you will find scientific study observations. But simply put it,cannabinoids work more effective and efficient in our bodies when they are combined together (full spectrum, RAW, broad spectrum products that include terpenes and other chemicals...), even chlorophyll that gives oil greenish color, plays a role in healing us!

In 1998, Professors Raphael Mechoulam and Shimon Ben-Shabat posited that the endocannabinoid system demonstrated an “entourage effect” in which a variety of “inactive” metabolites and closely related molecules markedly increased the activity of the primary endogenous cannabinoids, anandamide and 2-arachidonoylglycerol.

One significant evidence of this effect was observed in a comparison study between pure CBD and richer extracts with mixed chemicals 27.1 mg/kg/d for purified CBD vs. only 6.1 mg/kg/d. for CBD-rich Cannabis extracts, a dose only 22.5% of that for CBD alone. Furthermore, the incidence of mild and severe adverse events was demonstrably higher in purified CBD vs. high-CBD extract patients (p < 0.0001), a result that the authors attributed to the lower dose utilized, which was achieved in their opinion by the synergistic contributions of other entourage compounds. Such observations support the hypothesis of greater efficacy for Cannabis extracts combining multiple anticonvulsant components, such as CBD, THC, THCA, THCV, CBDV, linalool, and even caryophyllene!

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